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Causes of Impotence and/or Erectile Dysfunction
Impotence is defined as the inability to achieve or maintain an
erection sufficient for mutually satisfying intercourse.
Recently the term Erectile Dysfunction has been interchanged with
Impotence. Erectile Dysfunction is defined as the following:
The inability to achieve
penile erection or to maintain an erection until ejaculation. Also
called impotence. The incidence of Impotence
or Erectile Dysfunction often correlates with a man's age, some 67% of men by the
age of 70 years old have some difficulties achieving an erection.
Stress also as a significant
impact on man's ability to perform. Over the last decade we have
seen a considerable rise in the incidence of impotence in men in
their mid thirties and even younger. Stress has been noted as an
important cause of impotence in this age group.
Impotence impacts more than
a man's sexual activity. The emotions and uncertainties that
coincide with this condition often have a significant effect on a
man's self-esteem, as well as, his relationship with his partner.
Although the incidence of Impotence increases with age, it is not an
inevitable result of aging. Impotence is a secondary condition
linked to many medical conditions.
Fortunately, there are now
very effective methods to treat impotence. For a detailed
description of the most recommended impotence treatment options by
Urologist (doctors that specialize in this type of medicine) please
visit the following webpage:
The first step in treating Impotence is that the individual
understands the psychology, physiology and anatomy responsible for
the ability to achieve and maintain an erection. If we can comprehend
these events than we can better understand the factors that are
responsible for Impotence and address the questions concerning treatment.
Normal Erectile Function
For something that appears so natural, an erection
is a rather complicated process involving the coordination of the
psychological, neurological and cardiovascular systems. The penis
becomes erect following a series of events. First, the nerves are
stimulated, a sensation known as arousal. No matter what the nature
of the stimulus, visual, mental or physical the brain coordinates
the following series of events:
- Nerve impulses transverse the length of the spinal
cord to the pudendal nerve and on to the penis. Smooth muscle
within the walls of the penile arteries respond by relaxing. Subsequently,
the penile arteries dilate allowing up to eight times more blood
to flow into the corpora cavernosum, (two parallel cylinders that
transverse the length of the penis).
- The cavernosum become engorged with blood expanding
and lengthening the penis. The expanding tissue then exerts a
positive pressure compressing the veins that normally empty the
blood from the penis, maintaining the blood in the penile tissue.
When ejaculation occurs or when arousal is discontinued the penis
returns to its non-erect state.

Causes of Impotence
Historically, when an individual consulted his physician
concerning Impotence he was usually informed there were no known
physiological answers concerning his condition. Today, a generation
of research has resulted in significant advances in both the diagnosis
and treatment of Impotence. Physicians now understand that approximately
85% of Impotence is attributable to physical/organic conditions
while only 15% is due to psychological or mixed origin (both psychological
and organic). Some important causes of physiological Impotence are
as follows:
Vascular Disease
Vascular
Disease is the leading cause of Impotence. Vascular disorders include
arteriosclerosis (hardening of the arteries), hypertension, hyper-cholestremia
and other conditions which interfere with the blood flow to the
penis. Additionally, "venous leakage", a condition occurring
when the penile veins are unable to constrict efficiently during
an erection, also contributes to poor erections. When these veins
"leak", blood escapes to the periphery resulting in a
poor erection.
Diabetes is another common cause
of Impotence. Approximately 50% of men with insulin dependent diabetes
experience some degree of ED after 55 years old. Diabetes results
in poor circulation and/or peripheral neuropathy. When the nerves
are involved, sexual stimuli are not transmitted appropriately to
or from the brain and Impotence develops.
Neurological diseases such as multiple
sclerosis, Parkinson's disease, spinal cord injuries and long term
effects of diabetes can also result in the disruption of the normal
sequence of events necessary for an erection to occur.
Endocrine System

Deficiencies in the Endocrine System are another source of Erectile
Dysfunction. Low levels of testosterone or thyroid hormone can interfere
with the stimulation process necessary in the erection sequence.
Excessive production of prolactin by the pituitary gland may contribute
to decreased levels of testosterone resulting in a lack of desire.
Diabetes once again enters the scenario as it is classified as an
endocrine disorder.
Prescription medications often cause
Impotence as a side effect. Some two hundred known medications fall
into this category including:
Antihypertensives medications specifically:
- beta-blockers e.g. Atenolol, Propanolol and Tenorium.
Diuretics medications e.g. HydroDiuril and Lasix.
- Ace Inhibitors/Calcium Channel Blockers medications
e.g. Vasotec®, Lotension®,
- Cardizem® and Norvasc® periodically cause
Erectile Dysfunction, however, they are generally represent an
excellent alternative medication for individuals with drug induced
Impotence.
Antidepressant/Antipsychotic medications
-of almost any label can also result in Erectile Dysfunction
e.g. Prozac®, Elavil®, Zoloft®, Thorazine® and Haldol®.
Note: Many other medications in a variety of classes can periodically
cause Impotence. If you take a prescription medication or an over-the-counter
medication, regularly, please consult with your physician. However,
never alter a dosage or discontinue a medication without the advice
of your physician.
Smoking and Impotence
Smoking as been linked to Impotence in numerous clinical
studies.
The most common causes of the organic component in
erectile dysfunction or impotence are vascular abnormalities associated
with atherosclerosis and diabetes mellitus. Atherosclerosis causes
40% of cases of erectile dysfunction, and in cases of diabetes mellitus
the prevalence of erectile dysfunction is 50%. Smoking is significantly
associated with the development of both atherosclerosis and diabetes
mellitus.
The Epidemiology and Pathophysiology of Impotence.
The Journal of Urology 1999 Jan; 161(1):5-11

After smoking two cigarettes, the diameter of the internal
pudendal artery narrows and the penile arteries almost completely
close. This evidence suggests that smoking can cause an acute vasospastic
constriction of the arteries in the penis. These observations are
supported by physiological evidence that nicotine causes acute peripheral
vasoconstriction. Acute Vasospasm of Penile Arteries in Response
to Cigarette Smoking. Urology 1990; 36(1):99-100
Aside from impotence, smoking as also been
linked to the following negative effect concerning male sexual health:
- Reduced volume of ejaculation
- Lowered sperm count
- Abnormal sperm shape
- Impaired sperm motility
LH-RH Analogs/Antiandrogen medications
and Impotence are medications are used in the treatment
of prostate cancer. They function by decreasing the production of
testosterone in the testes and adrenal glands, which decrease in
testosterone often results in Erectile Dysfunction.
Chemotherapy/Radiation and Impotence therapy
is also a significant contributors to Impotence. These drugs/treatments
are used in the treatment of cancer.
Substance Abuse and Impotence can
also negatively effect male potency. The chronic use of cocaine,
marijuana, alcohol, steroids etc. often results in Erectile Dysfunction,
as well as a decrease in desire. Excessive tobacco use can also
attribute to Impotence by accentuating the effects of other risk
factor such as vascular disease or hypertension.
Radical Pelvic Surgery and Impotence
also result in Erectile Dysfunction. Surgical procedures involving
the prostate gland, bladder or colon may interfere with the nerves
involved in the erectile response. Radiation therapy for cancer
may also effect the erectile process.
Psychological Impotence is usually
diagnosed when no physical causes can be defined. Pure psychological
Impotence usually occurs suddenly without warning as opposed to
physical ED that may gradually develop over the years.
Some common causes of psychological Impotence are
as follows:
- Performance anxiety is one of the most common causes
of psychological Impotence. When a man feels pressured to achieve
or maintain an erection, he will commonly become anxious and nervous
when in a sexually demanding situation. Stress increases the body's
production of catecholamines such as adrenaline and nor- adrenaline,
which act as erection inhibitors. The release of these inhibitors
further contributes to failure resulting in more anxiety. Therefore,
the cycle begins, increased stress resulting in increased catecholomines
that further inhibits the erectile process.
- Depression is another cause of psychogenic Impotence.
Unfortunately, many of the popular antidepressant medications
(for a list see prescription medications in the next section)
have side effects which include erectile failure.
Anatomical Deviation of the Penis and Impotence
Anatomical Deviation of the Penis, known as Peyronie's Disease,
may also cause impotence. This condition usually develops from an
inflammatory process and results in fibrous scaring of the penis.
The cause of this process is not yet understood; however, when an
erection does occur, there is a bending of the penis secondary to
the scar tissue. This curvature may interfere with erectile capacity
and/or ejaculation.
Impotence Treatment
Options
Until recently, individuals who
sought medical treatment for Impotence were told "It's all in your
head". Physicians labeled these individuals with a psychological
disorder and they were referred to counseling. Today, there are many
treatment options available. The treatment option you choose should
be specific and responsive to your needs and expectations as well as
your partners.
Medication Information -currently there
are several oral medications for the treatment of impotence
including
Viagra,
Cialis,
Levitra
and
Uprima.
Simply click on the any of the
following popular impotence treatment medications for detailed
information:
Mechanism of Action of the
Various Impotence Medications:
The physiologic mechanism of erection of the penis
involves release of nitric oxide (NO) in the corpus cavernosum during
sexual stimulation. NO then activates the enzyme guanylate cyclase,
which results in increased levels of cyclic guanosine monophosphate
(cGMP), producing smooth muscle relaxation in the corpus cavernosum
and allowing inflow of blood. Some Medication Information enhance
the effect of nitric oxide (NO) by inhibiting phosphodiesterase
type 5 (PDE5), which is responsible for degradation of cGMP in the
corpus cavernosum. When sexual stimulation causes local release
of NO, inhibition of PDE5 by sildenafil causes increased levels
of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation
and inflow of blood to the corpus cavernosum.
Some impotence medications stimulate dopamine receptors
in the hypothalamus and mid brain regions. Subsequently, once sexual
stimulation as occurred an excitatory signal is transmitted via
the spinal cord to stimulate parasympathetic activity in the pelvic
region that results in smooth muscle relaxation in the walls of
the arteries supplying the penis. The relaxation of walls of these
arteries allows the arteries to expand so more blood can flow to
the region, hence, improved erections.
Other impotence medications exert their action by effecting
two enzymes, Cyclic guanosine monophosphate (cGMP) and phosphodiesterase
type 5 (PDE5) that play important roles in erectile function. Sexual
stimulation triggers the local release of nitric oxide (NO) from
nerves and endothelial cells in the penis. NO stimulates an enzyme
that catalyzes formation of cGMP from the nucleotide guanosine 5-triphospate
(GTP) in the penile blood vessels and corpus cavernosum walls.
The cGMP causes vasodilation of arteries, allowing
the influx of blood into the corpus cavernosum. Increased blood
flow into the penis causes the erectile tissue to expand. When the
erectile tissue has expanded sufficiently, the veins draining the
corpus cavernosum become compressed. This decreases the outflow
of blood from the penis, and the blood remains in the corpus cavernosum
to keep the penis erect.
The enzyme PDE5 eventually causes degradation of the
cGMP, and the erection ends.
Additional Impotence Treatment
Options
Herbal
Approaches for the treatment of impotence have become very
popular as an initial treatment for Impotence. Herbal supplements
for the treatment erectile dysfunction should contain a combination
of the following ingredients: Yohimbe (bark), Maca (root), Horny
Goat Weed (leaf), Saw Palmetto (berry), Schizandra (berry), Guarana
(seed) Tribulus Terrestris (aerial part), Ashwagandha (root), Asparagus
Racemosus (aerial part), Ginger (root) Cayenne Pepper (berry), L
Tyrosine, and L Histidine. Physicians' Select Male Enhancement
capsules provide the most complete ingredients for the herbal
treatment of erectile dysfunction.
Penile
Injection Therapy: treatment of impotence uses a hypodermic
needle to inject medication that is a mixture of papaverine, phentolamine
and prostoglandin into the side of the penis. The medication relaxes
the smooth muscle tissue of the penis allowing for an erection.
These injections can be painful, result in scare tissue formation
at the injection site and cause priapism, the prolonged and painful
engorgement of the penis).
Urethral
Inserts: treatment of impotence consists of a disposable
applicator, small enough to fit into the urethra. The applicator
is inserted into the urethra approximately one inch and the prostaglandin
E-1 medication is released. As a result, an erection occurs lasting
30-60 minutes. Patient acceptance is still an issue secondary to
expense and the low success rate as compared to other treatments
for Impotence.
Hormonal
Therapy: Impotence treatment is used to treat the small
percentage of individuals who have abnormally low levels of testosterone.
During the initial consultation, a physician will likely order LH
and Prolactin hormone test to exclude other causes of low testosterone
levels. If appropriate, testosterone is available in a transdermal
adhesive patch.
Vascular
Surgery: Impotence treatment may involve both the arterial
and venous systems. Venous ligation has been reported to be effective
in patients with venous leakage. However, it is often difficult
to diagnose individuals with this condition with the current testing
capabilities; therefore, it is difficult to predict their outcome
prior to surgery. Arterial re-vasculation procedures are limited
to congenital or traumatic vascular abnormalities. Similar to venous
testing, complete standardization diagnostic testing has not been
established, so difficulties persists in predicting surgical results.
Penile
Implants: Impotence treatment requires surgical insertion
of a prosthetic device. Three forms of penile prosthesis are currently
available flexible, malleable and inflatable. Flexible or Malleable
rods consist of two semi-rigid, flexible rods that make the penis
firm enough for intercourse. There are also inflatable prosthetic
devices that produce a more natural erection. When an erection is
desired the pump (located in the scrotum) is squeezed, this in turn
inflates a cylinder, which creates an erection.
Following intercourse, the pump is released and the penis returns
too normal. These devices have been associated with postoperative
infections, mechanical failure, silicon particle shedding and the
risk of the initial surgery.
Psychotherapy
and/or Behavioral Therapy: Impotence treatment have been
found to be beneficial in treating Impotence. Although the majority
of causes of impotence are physical, there are quite frequently
underlying psychosocial factors involved as well. Psychotherapy
and/or behavioral therapy may be helpful in individuals whom no
organic cause for Impotence has been detected. Therapy often focuses
on complications surrounding performance anxiety, dysfunctional
relationships, loss of a partner, psychotic disorders, substance
abuse, etc.
Final Notes, Impotence Treatment Options
In conclusion, more doctors recommend either Viagra or Cialis
for their patients who need an impotence treatment
While Viagra remains the most prescribed
impotence treatment medication, Cialis represents the longest lasting
impotence treatment medication, the erection
enhancement benefits of Cialis can last up to thirty-six hours
following a single dose.
We now offer detailed information concerning these two impotence
treatment medications
Viagra and,
Cialis.
For more information concerning
Viagra and/or Cialis simply click on the following:
Free Viagra Online Impotence Treatment Consultation (click here for details).
Free
Cialis Online Impotence Treatment Consultation (click here).
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