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Cause of Hair Loss, Thinning Hair, Baldness
Normally,
you will lose on average between 40-100 hairs per day of the
100,000 hairs present on the scalp. During any given time, 85-90
percent of an individuals hair is in the growing phase advancing in
length by 1/2 -1 inch per month. Hair can continue to grow from 2-6
years, when the growth phase ends the hair follicle starts a 2-6
month phase of resting and then shedding. Usually, only 10-15
percent of an individual's hair is in the resting or shedding phase
at any given time. Randomly, new hair follicles begin to replace the
shedding follicles producing a healthy cycle. However, in cases of androgenetic allopecia this natural cycle is disrupted.
Ninety-five
percent of hair loss is attributable to androgenetic alopecia, more
commonly known as hereditary hair loss or male pattern baldness.
Most research of late has focused on a genetic predisposition and
the presence of dihydrotestosterone (DHT). Every hair has a genetic
predisposition, the gene that determines whether an individual will
be susceptible to androgenetic alopecia is located on non-sex
chromosomes that determine the genetic makeup of all cells.
Researchers believe that DNA is somehow responsible for the
increased sensitivity of hair follicles to the hormone DHT. This
hormone results from the breakdown of testosterone by an enzyme
called alpha-5 reductase.
DHT causes the hair follicle to atrophy, reducing in size until only
vellus hair is produced. Vellus hairs are short fine non-pigmented
hairs which are difficult to see. As the diameter of the hair shaft
continues to decrease in size the sebaceous glands continue to
secrete the same volume of sebum (fats and oils which lubricate the
hair). This results in an oily scalp and subsequently flatter hair.
The process continues until the vellus hair is no longer produced
and individuals develop the characteristic hair loss pattern.
More doctors
recommend Propecia to decrease the amount of DHT (known cause of
hair loss) than any other hair loss treatment.
Propecia is the most
effective medication for the treatment of hair loss secondary to
increased levels of DHT. Extensive hair loss research has revealed
that men who suffer from male pattern hair loss have increased
levels of dihydrotestosterone (DHT). DHT is produced from
testosterone through the activity of 5-alpha-reductase enzyme.
Propecia inhibits 5-alpha-reductase, thus, blocking the formation of
DHT preventing hair loss by interrupting a key element in the
development of male pattern hair loss.
Additional
Causes of Hair Loss
Although the majority of hair loss is secondary to androgenetic
alopecia there are other significant causes of hair loss that should
be addressed including the following:
- Alopecia areata
is an immune system disorder that effects the hair follicles
ability to produce hair. A sudden loss of hair from a small area
is a common presenting symptom. Advanced forms of the disorder
include alopecia totalis, where all hair on the head is lost and
alopecia universlis, which results in the absence of all body
hair.
- Pregnancy is
a period when hormones can fluctuate considerably in women. While
pregnant women are not especially prone to lose hair. However, two
to three months post-partum, a significant number of hair
follicles will enter the resting phase. Some women will experience
considerable hair loss during this time for approximately one to
six months. This condition is self-limiting and reverses in most
cases.
- High fever is
another cause of alopecia. Four to six weeks following a high
fever or significant infection individuals may notice a
significant amount hair loss. This condition is self-limiting and
reverses in most cases.
- Nutritional
deficiencies can be a rare cause of hair loss. Some
vegetarians, individuals on fad diets, etc. who severely limit
their intake of proteins may lose a significant amount of hair. In
protein deficiencies the body will strive to save protein by
shifting the hair follicles into the resting phase. Extensive hair
loss is then demonstrated several months later. Iron deficiency is
also a rare cause of hair loss. The process is reversed with the
proper diet.
- Thyroid disease
is another disorder associated with hair loss. Individuals with
hyperthyroidism or hypothyroidism may experience hair loss. The
diagnosis is usually established by a patient's history combined
with laboratory results. Hair loss associated with a thyroid
disorder is usually reversible with the proper medication.
- Prescription
medications are another source for hair loss. Some
examples of medications that are known to cause hair loss include:
blood thinners, gout medications, anti-depressants, arthritic
medications, hypertension medications, birth control pills, high
doses of vitamin A, chemotherapy/radiation, etc.
- Major surgery
may present excessive stress on the system that can result in hair
loss. Hair loss is generally noticed one to three months following
the surgery. The condition will usually reverse itself unless the
individual has a chronic illness.
- Ringworm of
the scalp, actually caused by fungus, begins with small patches of
scaling that subsequently spread resulting in broken hair. This
condition is contagious and is common in school aged children. The
condition is resolved with oral or topical medication.
- Chemical products
such as dyes, bleaches, tints, straighteners, perms, chlorine,
etc. can all damage hair. These products when used excessively can
dry hair out causing it to break at the roots.
- Traction alopecia
is the loss of hair secondary to constant pulling as seen in tight
ponytails, hair weaves, braids, etc.
Cause of Hair Loss Conclusions
Remember, some 95% of male pattern hair loss
is secondary to androgenetic alopecia, more commonly known as
hereditary hair loss or male pattern hair loss resulting in
increased levels of DHT.
Propecia inhibits
5-alpha-reductase, thus, blocking the formation of DHT preventing
hair loss by interrupting a key element in the development of male
pattern hair loss. Propecia's ability to effectively limit this key
factor that contributes to hair loss is why Propecia is the most
prescribed hair loss treatment by doctors throughout Europe.
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